Tesamorelin
Growth hormone–releasing hormone (GHRH) analogue · Pre-filled pen
Tesamorelin is a stabilised analogue of growth-hormone-releasing hormone (GHRH) that binds pituitary GHRH receptors and stimulates the body's own GH secretion through the natural hypothalamic–pituitary axis. It is best known and regulator-approved for reducing excess visceral adipose tissue in a specific HIV-associated condition, with related effects on glucose–lipid markers. Its use for general lean-mass support or anti-ageing is off-label and not established by outcome trials.
Studied use areas
- Research into stimulation of the endogenous GH axis
- Visceral-adiposity and body-composition research
- Lean-tissue-preservation research
- Glucose–lipid metabolic-marker research
Safety & status
- Educational information only — not medical advice; use requires physician supervision
- Prescription-only medicine; approved only for a specific HIV-related indication, other uses are off-label
- Can affect glucose regulation and fluid balance and is not suitable in certain conditions, so clinical screening is essential
- Suitability, indication and monitoring are determined by the treating physician
⚕ Clinical note: This card is educational and is not medical advice, a protocol or a promise of results. Tesamorelin is a prescription-only medicine; any use must be individualised and supervised by a qualified physician.
Evidence: Approved for a specific HIV-related indication; investigational / off-label (Grade C) for lean-mass and GH-axis goals · References: GHRH-analogue clinical-trial literature; EMA/MHRA/FDA product information; peer-reviewed endocrinology and body-composition studies



