SS-31 (Elamipretide)
Mitochondria-targeting tetrapeptide (elamipretide / SS-31) · Pre-filled pen
SS-31 (elamipretide) is a mitochondria-targeting peptide studied for its interaction with cardiolipin on the inner mitochondrial membrane, where it is associated with stabilising energy production and reducing reactive oxygen species (ROS). In skin-health contexts it is investigated for mitochondrial-function and oxidative-stress endpoints relevant to cellular resilience and ageing. It remains an investigational compound and is not an approved skin treatment.
Studied use areas
- Mitochondrial-function endpoints in skin and other cells
- Oxidative-stress and ROS-reduction research
- Cellular energy and resilience support
- Anti-ageing signalling endpoints (investigational)
Safety & status
- Investigational compound — not an approved medicine for skin or other uses
- Injection-site reactions have been reported; long-term aesthetic safety is not established
- Requires physician assessment before use
⚕ Clinical note: This is educational information only and not medical advice. SS-31 (elamipretide) is investigational and unapproved for aesthetic use; any use must be assessed and supervised by a treating physician, who determines suitability on an individual basis.
Evidence: Investigational — mechanistic and clinical-trial data, not approved · References: Peer-reviewed mitochondrial-medicine literature; Clinical-trial reports on elamipretide; EMA/MHRA regulatory and product information
