Skip to content
Verified quality
Contact support
Physician recommendation required · Educational information, not medical advice
Dripfy
PT-141 (Bremelanotide)
≥99% HPLCPre-filled pen

PT-141 (Bremelanotide)

What it is?

PT-141 is a melanocortin-pathway peptide studied for its role in central arousal and desire signalling. It is positioned to influence libido through CNS mechanisms, rather than relying solely on peripheral vascular modulation.

Dripfy Advantage

  • Receptor engagement: Targets melanocortin receptors implicated in sexual motivation and arousal signalling (CNS-focused pathway).
  • Neuro-signalling modulation: Associated with regulation of neural circuits linked to sexual response, supporting desire-related endpoints in controlled settings.
  • Non-vascular primary mechanism: Positioned as a central-acting approach, distinct from strategies that primarily target blood-flow dynamics.
  • Cross-sex applicability: Commonly framed for both male and female sexual wellness research endpoints, depending on protocol design and screening.

Clinical Applications & Therapeutic Potential

  • Libido and arousal endpoints: Potential support for improved desire and arousal-response markers in CNS-mediated sexual function protocols.
  • Sexual satisfaction outcomes: Potential improvement in sexual satisfaction–related endpoints in appropriately selected cohorts (context-dependent).
  • CNS-driven dysfunction frameworks: Positioned for cases where reduced libido is linked to neuro-signalling factors rather than purely mechanical drivers.
  • Male and female protocols: Often discussed for broad applicability, with outcomes dependent on baseline neuroendocrine context and protocol controls.

Composition & Formulation

  • Peptide Content: 10 mg PT-141 (Bremelanotide)
  • Vehicle: Proprietary pH-balanced buffer solution
  • Delivery System: Pre-filled, multi-dose, closed-system pen
  • Total Volume: 3 mL
  • Purity: ≥99% by HPLC/MS
€478

Submit an enquiry and we arrange the consultation, physician review and shipping. Physician recommendation required; not medical advice.

Purity
≥99%
Form
Pre-filled pen
Download Certificate of Analysis
Certificate of Analysis available on request

Important medical notice

  • A physician recommendation is mandatory before use.
  • The information on this website is educational only and is not medical advice, diagnosis, or treatment.
  • Always consult a qualified physician before starting any peptide.
  • Dosing is individualised and determined by your treating physician.

Peptide Practice Guide

Each card summarises what the peptide is studied for and its evidence strength. It is not a recommendation. Dosing and suitability are decided by your physician.

PT-141 (Bremelanotide)

Centrally acting melanocortin receptor agonist · Pre-filled pen

B· Moderate evidence

PT-141 (bremelanotide) is a centrally acting melanocortin receptor agonist. It engages melanocortin receptors — MC4R in particular — within brain circuits that govern sexual motivation and arousal, so its primary action is on desire signalling in the CNS rather than on peripheral blood flow. This central mechanism is what distinguishes it from vasodilator-type approaches to sexual function.

Studied use areas

  • Female hypoactive sexual desire disorder (HSDD), the approved indication for bremelanotide
  • Central (brain-driven) sexual desire and arousal signalling
  • Sexual-wellness research in both women and men, depending on screening
  • As an approach distinct from blood-flow-focused erectile therapies

Safety & status

  • Prescription-only in the EU/UK; supply and use require a qualified prescriber
  • Commonly reported effects include nausea, flushing and headache; transient rises in blood pressure and small heart-rate reductions have been described, so cardiovascular screening matters
  • Melanocortin activation can trigger focal darkening of skin or gums (hyperpigmentation) in some users
  • Not suitable for self-directed use; suitability and any regimen are decided case by case by the treating physician

Clinical note: This card is educational and is not medical advice, a diagnosis, or a recommendation to use any product. Bremelanotide is a prescription medicine that must be assessed, prescribed and monitored by a qualified physician; never self-source or self-administer it.

Evidence: Grade B — approved as bremelanotide (Vyleesi) for premenopausal HSDD, with supporting randomised controlled trials; benefit is real but modest and patient-selected. · References: EMA/MHRA/FDA product information for melanocortin receptor agonists; Peer-reviewed randomised controlled trials on bremelanotide for HSDD; Pharmacology reviews of centrally acting sexual-medicine agents

Related peptides